{Antiviral, Cold Sores} 

Meglumine acridоnacetate 
Cycloferon  Tablets 150 mg  

Different dosages are possible. Ask for prices. 

• Liniment 5%: 5 ml (meglumine acridоnacetate) 
• Liniment 5%: 30 ml (meglumine acridоnacetate)
• Tablets 10/20/50 pcs: 150 mg (meglumine acridоnacetate)

★Pharmachologic effect

Low-molecular-weight interferon inducer, has antiviral, immunomodulatory and anti-inflammatory effects. The main target cells are T- and B-lymphocytes, stimulates the production of interferons alpha, beta and gamma (up to 60-80 U / ml and above) by leukocytes, macrophages, epithelial cells, as well as tissues of the spleen, liver, lungs, brain. Penetrates into the cytoplasm and nuclear structures, activates the synthesis of "early" interferons. The immunomodulatory effect is expressed in the correction of the body's immune status in immunodeficiency states of various origins. Differs in low toxicity and absence of mutagenic, teratogenic, embryotoxic and carcinogenic effects. It is active against tick-borne encephalitis, influenza, hepatitis, herpes, cytomegalovirus, HIV, various enteroviruses, chlamydia viruses.

★Pharmacokinetics

When taken orally, the maximum permissible dose Cmax in the blood is reached after 1–2 hours, the concentration gradually decreases after 7 hours, after 24 hours it is found in trace amounts. Passes through the blood-brain barrier. The half-life (T½) is 4-5 hours. Does not cumulate with prolonged use.

★Indications

As part of complex therapy and depending on the dosage form:

• infections - HIV-related, cytomegalovirus, herpes;
• urogenital, including chlamydia, neuroinfections (serous meningitis, tick-borne borreliosis, multiple sclerosis, arachnoiditis and others), acute and chronic viral hepatitis (A, B, C, D);
• immunodeficiency states of various etiologies (postoperative period, burns, chronic bacterial and fungal infections, including bronchitis, pneumonia);
• peptic ulcer of the stomach and duodenum;
• oncological diseases;
• rheumatoid arthritis;
• degenerative-dystrophic diseases of the joints (deforming osteoarthritis and others);
• skin diseases (neurodermatitis, eczema, dermatosis);
• flu and acute respiratory viral infections;
• genital herpes, urethritis and balanoposthitis (nonspecific, candidal, gonorrheal, chlamydial and Trichomonas etiology), vaginitis (bacterial, candidal);
• prevention of influenza and acute respiratory diseases in children aged 4 years and older.

Contraindications

• Hypersensitivity;
• cirrhosis of the liver (in the stage of decompensation);
• pregnancy;
• lactation;
• children's age (up to 4 years old).

Pregnancy and breastfeeding

FDA category of action on the fetus - N.

The drug is contraindicated for use during pregnancy and lactation (breastfeeding).

★Method of administration and dosage

The dosage regimen is individual, depending on the indications, therapy regimen and dosage form.

★Application methods

Inside, once a day, 30 minutes before meals, without chewing, squeezing 0.5 glasses of water, in age dosages:

children 4–6 years old: 150 mg (1 tablet) per dose;

children 7-11 years old: 300-450 mg (2-3 tablets) per appointment;

adults and children over 12 years old: 450-600 mg (3-4 tablets) per dose.

It is advisable to repeat the course 2-3 weeks after the end of the first course.

In adults:

1. When treating influenza and acute respiratory diseases, the drug is taken on the 1st, 2nd, 4th, 6th, 8th day (course of treatment - 20 tablets). Treatment should be started at the first symptoms of the disease.

For severe flu, six tablets are taken on the first day. If necessary, symptomatic therapy is additionally carried out (antipyretic, analgesic, expectorant drugs).

2. In case of herpes infection, the drug is taken for 1, 2, 4, 6, 8, 11, 14, 17, 20, 23 days (course of treatment - 40 tablets). Treatment is most effective when the first symptoms of the disease appear.

In children from the age of four:

1. In case of influenza and acute respiratory diseases, the drug is taken in age doses on days 1, 2, 4, 6, 8, 11, 14, 17, 20, 23. The course of treatment is from 5 to 10 receptions, depending on the severity of the condition and the severity of clinical symptoms.

2. In case of herpes infection the drug is taken on the 1st, 2nd, 4th, 6th, 8th, 11th, 14th days of treatment. The course of treatment may vary depending on the severity of the condition and the severity of clinical symptoms.

3. For urgent non-specific prophylaxis of influenza and acute respiratory diseases (in direct contact with patients with influenza or acute respiratory infections of another etiology, during an influenza epidemic): on the 1st, 2nd, 4th, 6th, 8th day. Then take a break of 72 hours (three days) and continue the course on 11, 14, 17, 20, 23 days. The general course is from 5 to 10 receptions.

★Side effects

Allergic reactions.

★Interaction

Compatible with all drugs used in the treatment of these diseases (including interferons, chemotherapeutic drugs).

Strengthens the action of antibiotics, antiseptics and antifungal drugs.

★Precautions

For diseases of the thyroid gland, treatment should be carried out under the supervision of an endocrinologist.

It is recommended to supplement the treatment of chronic herpes infection with other antiviral drugs and vaccines.

Shows high efficiency in rheumatic and other systemic diseases of the connective tissue, suppressing autoimmune reactions and providing anti-inflammatory and analgesic effects.

https://pubmed.ncbi.nlm.nih.gov/23863208/

☆Different packaging design options are possible. Packing may be different, depends on the manufacturer. The composition of the tablets is the same. Medicine is made for the Russian market and has a the same design. Read the instructions on the Internet. Consult a doctor. Consider indications and contraindications for use.

☆Import duties, taxes, and charges are not included in the item price or shipping cost. These charges are the buyer's responsibility. Please check with your country's customs office to determine what these additional costs will be prior to bidding or buying.

☆Attention: Due to the ongoing worldwide pandemic, severe postal delays will occur. So we use registered post with Tracking Number. But please be kind enough to wait for about 2-3 months. We will make sure that you will get your package as soon as possible. 

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